Firstly - do not despair! It's not all in your head as has been the mainstream view of the UK medical establishment for many years. The Government working group concluded last year concluded that these are 'bone fide' organic diseases & not psychological or phsyciatric deseases, although the majority of the UK medical system persists in treating them as such. In time I will post a link to this report & the background behind it, but in the meantime you may find help & support in the Threads on this forum and Allergies & Arthritis forums, as something may ring true there. From a symptom point of view - I believe they are related & from a physioligical point of view I suspect they are linked via underlying food & environmental sensitivity, intolerance/allergy. Have lots of tips for ME & Fibromyalgia & in time will try & get them together and post them here, but here's a couple of key ones to try. * Sleep with your legs raised, making sure you support behind the knees, so as not to over extend them. Studies have showed that folks with fibro have a greater body water content, but less blood volume. Other studies have shown that there are certain common areas of the brain that are not getting a good supply of blood. Some of the classic symptoms support this - i.e. poor memory, brain fog (inablility to focus & concentrate), poor quality of sleep ( that no drug as yet has been able to improve), etc. Sleeping with legs raised will encourage better blood perfusion to those areas of the brain. * Regularly get your thoracic spine moving with stretches in all directions (flexion, extension, side bending & twisting) & manipulation i.e. osteopathy (although an osteopath should do much more than just manipulate). I can pretty much guarantee that the thoracic spine will be inflamed & you may not be aware of it (this area is a low priority when it comes to pain sensory input to brain). Also, this can create havoc with the function of your internal organs, although it's a bit chicken & egg. Also, the muscles become fiberous due to their tendency to fatigue easily, so they try & work anaerobically (without oxygen) & they shorten as a compromise, as the little energy in the system is prioritised elsewhere. Keeping moving will improve circulation & reduce inflammation, so even if it's the last thing you feel like doing - get moving, but don't over do it! Little & often is the key. Lots more stuff to come - prompt me if necesary. Good luck & don't give up! Andrew.